For those who have peanut allergies, we learn something new about our bodies each day. In recent studies conducted by scientists, severe peanut allergies could stem from the stomach and gut. These new findings could possibly find treatment. In this article, you will learn how immune cells play a big role in peanut allergies.

Results from the Study

Research began by studying RNA in cells from the esophagus, stomach, and duodenum samples. Cells use this genetic material to make proteins, including specific types of antibodies. The various RNA molecules were counted up in samples by the researchers which concluded on which antibodies were present in the system and where. This method lets scientists estimate how many cells were churning these IgE antibodies out of the system.

The study for peanut allergies focused on a rare antibody called IgE. This antibody is present in small numbers, in which IgE senses invaders such as parasites, causing massive immune reactions designed to purge the threat. But, for people with peanut allergies, the antibody goes rogue and targets harmless substances, such as peanut proteins. 

What Does This Mean for the Future?

Scientists who conducted this experiment, plan to study IgE levels in some of the same patients with peanut allergies after they’ve participated in the clinical trial aimed at easing their allergies. It turns out this sensing process of the peanut prevents IgE from setting off a reaction in the body, therefore it may be a way to restrain peanut allergies once and for all.

As of right now, researchers don’t know when these antibody-producing cells first arrive in the stomach and intestines. They also don’t know if the cells would start to disappear as allergies fade in the near future.